Loxagen is developing first-in-class therapeutics for diseases with strong unmet needs. Our team is comprised of experienced industry personnel who have taken multiple drugs to the clinic and world-renowned clinicians. Our lead is the first oral anti-thrombotic that prevents clotting without risk of bleeding. Our secondary program is the first oral therapy for Type 1 Diabetes.
Experienced Executive team
The team has led 6 IND submissions,3 New Drug Applications, and has executed over $4B in prior pharma partnerships
Fast Follower
First gen ALOX12 inhibitor, validated in Phase 2 trials with outstanding safety and efficacy data
One and Done
A raise of $15M completes Phase 1 A/B for HIT. An additional $15M completes Phase 2 for the first oral treatment for HIT
Large market and partner pull
Targeting a $4B exit on a $30M investment.
Deep scientific and development expertise
Kalidip Choudhury, Ph.D
CEO/Co-founder
20 years pharma Bus Dev
$4B plus in pharma partnering
(incl. orphan disease partnerships)
Robert Martin, Ph.D
COO
40 years in pharma development
5 IND, 2 NDA
Roche, Cymabay
Lynda Szczech, MD
CMO
>30+ years in pharma.
Fibrogen, PPD, Duke
Robert Miller
CFO
40+ years in pharma
Sonoma Pharma, Cerus Corp
Dawn McCullough
EVP, Clinical Ops
>40 Clinical trials
Biogen, Novartis
Scientific Founders
Michael Holinstat, Ph.D
Professor, University of Michigan
Director, Cardiovascular Research Network. Leading authority on platelet biology
Theodore Holman, Ph.D
Professor, UC Santa Cruz
30 years of LOX expertise
Clinical Advisors
Bertram Pitt, M.D
Director, Division of Cardiology, University of Michigan.
Marc Pfeffer, M.D, Ph.D
Distinguished Professor of Medicine, Heart and Vascular Center, Harvard University.
Raghu Mirmira, M.D, Ph.D
Director, Diabetes Center, University of Chicago.
Linda DiMeglio, M.D
Chief, Pediatric Endocrinology, Indiana University