Loxagen is developing first-in-class therapeutics for diseases with strong unmet needs. Our team is comprised of experienced industry personnel who have taken multiple drugs to the clinic and world-renowned clinicians. Our lead is the first oral anti-thrombotic that prevents clotting without risk of bleeding. Our secondary program is the first oral therapy for Type 1 Diabetes.

Experienced Executive team

The team has led 6 IND submissions, 3 New Drug Applications, and has executed over $4B in prior pharma partnerships

Fast Follower

First gen ALOX12 inhibitor, validated in Phase 2 trials with outstanding safety and efficacy data

One and Done

A raise of $15M completes Phase 1 A/B for HIT. An additional $15M completes Phase 2 for the first oral treatment for HIT

Large market and partner pull

Targeting a $4B exit on a $30M investment.

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Deep scientific and development expertise

Kalidip Choudhury, Ph.D

CEO/Co-founder

  • 20 years pharma Bus Dev
  • $4B plus in pharma partnering (incl. orphan disease partnerships)

Robert Martin, Ph.D

Robert Martin, Ph.D

COO

  • 40 years in pharma development
  • 5 IND, 2 NDA
  • Roche, Cymabay

Lynda Szczech, MD

CMO

  • >30+ years in pharma.
  • Fibrogen, PPD, Duke

Robert Miller

CFO

  • 40+ years in pharma
  • Sonoma Pharma, Cerus Corp

Dawn McCullough

Dawn McCullough

EVP, Clinical Ops

  • >40 Clinical trials
  • Biogen, Novartis

Scientific Founders

Michael Holinstat, Ph.D

Professor, University of Michigan

Director, Cardiovascular Research Network. Leading authority on platelet biology

Theodore Holman, Ph.D

Professor, UC Santa Cruz

30 years of LOX expertise

Clinical Advisors

Bertram Pitt, M.D

  • Director, Division of Cardiology, University of Michigan.

Marc Pfeffer, M.D, Ph.D

  • Distinguished Professor of Medicine, Heart and Vascular Center, Harvard University.

Raghu Mirmira, M.D, Ph.D

  • Director, Diabetes Center, University of Chicago.

Linda DiMeglio, M.D

  • Chief, Pediatric Endocrinology, Indiana University

Magdy Selim, M.D

  • Director of Stroke Center, Harvard University.

Roche
Novartis
Biogen
Harvard University
Duke University
The University of Chicago
Johns Hopkins University
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